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| Reagent | Conditions | Product type | Example (from 1-bromopropane) | |---------|------------|--------------|-------------------------------| | NaOH(aq) | warm | Alcohol (substitution) | propan-1-ol | | KCN(aq/eth) | heat, reflux | Nitrile (+1C) | butanenitrile | | NH₃(excess) | heat in sealed tube | Amine | propylamine | | KOH(ethanolic) | heat | Alkene (elimination) | propene | | AgNO₃/ethanol | room temp → warm | Halide ppt (for rate order) | AgBr (cream) |
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The Reagent: Water (often with silver nitrate – see Section 5). The Product: Alcohol + Hydrogen halide.
This is a slower, less vigorous reaction than with OH⁻.
Example: 2-chlorobutane with water.
Exclusive Insight: This reaction is reversible. In the lab, we drive it forward by adding a base (like NaOH) to neutralize the HX produced.
Strong, bulky bases favor elimination over substitution.
Typical reagent: Ethanolic KOH (or NaOH in ethanol), heat.
Elimination produces alkenes.
✅ Example:
2-bromopropane + ethanolic KOH → propene + KBr + H₂O